
High-Dose Capsules
98% salt. The fill is the dose. A 10:1 bark extract will not reach it.

Berberine hydrochloride at about 98% is a single alkaloid salt, not a goldenseal powder and not a barberry ratio extract. Commercial berberine is produced from several Berberis and related barks, then crystallized.
It is used in glucose and lipid-style capsules at hundreds of milligrams. That dose is in the range where drug interactions matter, including with cyclosporine and some CYP substrates.
When buying, specify berberine HCl 98% by HPLC, residual solvents, and the botanical source if your file requires one.
| Product Name | Berberine Hydrochloride Powder | Botanical Name | Phellodendron spp. bark |
|---|---|---|---|
| Part Used | Bark | Specification | 98% Berberine HCl |
| Appearance | Yellow Crystalline Powder | Test Method | HPLC |
| MOQ | 1kg | Shelf Life | 2 years |
| Ingredient | Berberine hydrochloride (Berberine HCl) | Extraction source | Cortex Phellodendri (Phellodendron bark) |
| CAS number | 633-65-8 | COA | Available |
| Certificate | ISO 22000, FDA, BRC, IFS, SGS, Kosher, Halal, Organic (EU), USDA, HACCP, ISO 9001 | Quality | Non-GMO, Non-irradiation, Allergen Free, BSE/TSE Free |
| Sample | 10-50 g sample for evaluation | OEM Service | Private labeling, customized packaging, capsules and tablets |
| Packaging | 1-5 kg / 25 kg (aluminum foil bag / fiber drum) |

98% salt. The fill is the dose. A 10:1 bark extract will not reach it.

Yellow and bitter. A coating is normal.

Goldenseal is a small berberine percent plus other alkaloids.

98% berberine HCl is a high milligram dose. A bark tea will not reach it.

High-dose berberine is watched for drug interactions. Keep the warning inside the destination rule.

Goldenseal is a whole extract. This is crystallized berberine hydrochloride.